Evolution of melanoma
The mutational landscapes of melanocytic neoplasms as they progress from the benign to the malignant state.
Pathways disrupted
Signaling pathways become disrupted in a stereotypical fashion during the progression of melanoma

The Shain laboratory has recently opened in the Department of Dermatology at the University of California San Francisco!

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The overaching goal of the Shain laboratory is to better understand the biology of melanoma. We use a variety of -omic approaches to delinate the genetic and transcriptomic alterations in melanocytic tissues. Recently, we have initiated single-cell based studies (both DNA- and RNA- single-cell sequencing). For more details related to ongoing projects, please reach out to the PI (Hunter Shain at [email protected]). Scientific positions at all levels are currently open. Please contact Hunter Shain for more details ([email protected]).